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hu zhang
虎杖
by: Joe Hing kwok Chu
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Source of picture: Taipei's Farmers Association 圖片來源﹕台北市農會
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Present Day
Applications: |
preventing thrombosis from arterial
endothelial damage |
| Pharmaceutical name: |
Polygoni Cuspidati Rhizoma |
| Latin botanical name: |
Polygonum cuspidatum Sieb. et Zucc.
P.reynoutria Makino;Reynoutia Japonica Houtt |
| Pron. in Japanese: |
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| Pron. in Korean: |
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| Pron. in Cantonese: |
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| Common Name: |
Japanese knottweed |
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Other Names:
別名﹕ |
chuan qi, ban zhang, suan zhang, huang yao zi,
chuan jun long, da chong zhang
川七.班杖.酸杖.黃藥子.川筋龍.大蟲杖
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| Distribution: |
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| Properties (characteristics):
性味﹕ |
slightly bitter, neutral
味微苦﹐性平 |
| Channels (meridians)
entered: 歸經﹕ |
liver, spleen
入肝﹐脾二經。 |
| Medical
Functions:
藥理﹕ |
Medical
Functions:
1. anti viral
2. anti leptospirosis
3. anti fungal
4. relaxes the bronchial
smooth muscles, expels phlegm, and
suppresses asthma and cough
5. lower blood pressure and lipids
6. stops bleeding in external injuries
7. inhibits pain
8. astringent
9. anti inflammatory
10. antibiotic, like: Pseudomonas
aeruginosa，Staphylococcus
aureaus，Moraxella
(Branhamella), catarrhalis，Streptococcal，Escherichia
coli.
藥理﹕
1。抗病毒
2。抗鉤端螺旋體
(leptospirosis)﹐
3。抗真菌
4。鬆弛支氣管平滑肌，而達鎮咳平喘,
袪痰止咳
5。降血壓及降血脂之作用
6。對外傷出血有明顯的止血作用
7。鎮痛
8。收斂
9。消炎
10。抗菌﹕如綠膿桿菌
Pseudomonas aeruginosa，金黃色葡萄球菌Staphylococcus
aureaus，
卡他球菌 Moraxella (Branhamella) catarrhalis，鏈球菌
Streptococcal，大腸桿菌Escherichia
coli,等
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| Actions & Indications: |
For jaundice, gall bladder stones, blood stasis with menses stoppage,
yeast infection, rheumatoid arthritis, physical injuries from impacts,
inflammation of the bronchi, lobar pneumonia, poisonous snake bites,
scalding injuries, acute hepatitis, urinary tract infection, boils, stoppage
of menses due to heat in the blood, breast cancer, menopausal bleeding
disorder.
黃疸，膽結石，經閉瘀阻,
帶下，風濕痛，跌扑損傷，支氣管炎，大葉性肺炎,
毒蛇咬傷，燙火傷，急性肝炎，尿道感染，瘡癤腫毒，血熱經閉，乳癰，崩漏。
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| Chemical ingredients:化學成份﹕ |
根和根莖含游離蔥昆及恩昆貳，主要為
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| emodin |
大黃素 |
| physcion |
大黃素甲醚[1,3] |
| chrysophanol |
大黃酚[1,2] |
| anthraglycoside A,
(physcion-8-O-β-D-glucoside) |
恩貳A即大黃素甲醚8-o-β-D-葡萄糖貳[4] |
| anthraglycoside B,
emodin-8-O-β-D-glucoside |
恩貳B即大黃素8-o-β-D-葡萄糖貳[3,
4]， |
| fallacinol |
迷人醇 |
| citreorosein |
6-羥基蘆薈大黃素 |
| questin |
大黃素-8-甲醚 |
| questinol |
6-羥基蘆薈大黃素-8-甲醚[5] 等。 |
| resveratrol,
3,4',5-trihydroxystilbene |
醇類化合物：白黎蘆醇即是3,4'.5-三羥基醇 |
| polydatin,
resveratrol-3-O-β-D-glucoside) |
虎杖貳即白黎蘆醇3-O-β-D-葡萄糖貳3,6], |
| protocatechuicacid |
原兒茶酸 |
| catechin |
右旋兒茶精 |
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2,5-dimethyl-7-hydroxychromone |
2，5-二甲基-7-羥基色酮 |
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7-hydroxyl-4-methoxy-5-methylcoumarin |
7-羥基-4-甲氧基-5-甲基香豆精 |
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torachrysone-8-O-D-glucoside |
決明恩酮-8-葡萄糖貳([5], |
| B-sitosterolglucoside |
3-谷甾醇葡萄糖貳[3] |
| glucose |
葡萄糖 |
| rhamnose |
鼠李糖[1] |
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polysaccharides |
多糖 [7]， |
| amino acid |
氨基酸12.99% |
| copper, iron, manganese, zinc,
potassium . |
銅 鐵﹐錳﹐鋅﹐鉀.[8] |
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| Dosage:
用量﹕ |
10 to 20 g per day;
concentrated extract: 0.5 to 2 g per day
每日10～20公克；濃縮中藥：每日0.5～2.0公克。 |
| Samples of formulae: |
(1) For vaginal
yeast infection: hu zhang 100g, water 1500
cc. Simmer down to 1000 cc. Strain. Cold down to bath water temperature. Use
for sitting bath. Use 10 to 15 minutes, once a day. 7 days is one therapy
cycle. Treated 30 patients. All healed.
(1)
真菌性陰道炎：虎杖根100g，加水1500ml，煎取1000ml，過濾，待溫，坐浴10～15分鐘，每日1次，7日為1療程，治療30例，全部臨床治愈。 |
| Modern Research: |
See abstract below |
| Cautions: |
not to use during pregnancy.
Large dosages and/or long term
usage can be toxic to kidneys.
大劑量或長期服用可能對腎臟有毒。
孕婦忌服。 |
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中國藥理
學與毒理學雜誌電子版 |
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虎杖有效成分3,4′,5-三羟基芪-3-β-D-葡萄糖貳的研究進展 |
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骆蘇芳 金行中 葉建锋 張佩文 |
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第一軍醫大學基礎部毒理學教研室 廣州 510515 |
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【摘要】總結了虎杖有效成分3,4′,5-三羟基芪-3-β-D-葡萄糖貳(虎杖晶Ⅳ)
近10年來的研究，評價了虎杖晶Ⅳ在防止動脉内皮損傷性血栓形成，改善休克微循環，提高休克大鼠存活率，減輕缺血再灌注，自由基，内毒素等造成的組織器官損傷，降血脂及抗脂質過氧化等方面的作用。提示虎杖晶Ⅳ可能成為治療血栓性疾病及改善休克微循環等方面一個有特色的新藥。
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Advances in research on
3,4′,5-trihydrostilbene-3-β-D-glucoside,an effective component from
Polygonum cuspidatum Sieb. et Zucc |
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Abstract
The advances in recent 10 years in
research on 3,4′,5-trihydrostilbene-3-β-D-glucoside (polydatin),
a effective component from Polygonum cuspidatum Sieb. et Zucc.,
were summarized in this paper. The actions of
polydatin, such as
preventing thrombosis from arterial endothelial damage, improving
microcirculation and increasing survival rate of shocked rats, alleviating
tissueorgan damage induced by ischemia-reperfusion, oxygen free radical and
endotoxin, decreasing hyperlipemia, suppressing lipid peroxide and so on
were evaluated. The review displays the pharmacologic base of
polydatin
in
treatment of thrombotic diseases and improvement of microcirculation in
shock, which enable
polydatin
to become a new characteristic drug. |
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Last update: May 8, 2004; 11:57 a.m. LA
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現代中藥辭典